It should be noted that in theory if one was to consistently suppress your natural estrogen levels for a long period of time, this would negatively impact your health, including your cholesterol. Due to the ability of Letrozole- to inhibit estrogen so much, this should definitely be a concern to most users. However the research that has focused on the relationship between use of letrozole and cholesterol levels is rather inconsistent in it's findings. Many studies have concluded that the compound is detrimental to both a user's HDL and LDL cholesterol levels, while other research has found no link. Obviously individuals are best served to monitor their cholesterol while using any compound via blood tests however barring that, letrozole should simply not be run for extended periods of time if at all possible. Doing so could cause serious medical complications.
Along with the issues related to blood lipids is the fact that many users complain that their libido is dramatically reduced when using the compound. This is related to the fact that estrogen is partly responsible for the regulation of an individual's sex drive. Since Letrozole- is so potent it can often drive estrogen levels too low and this inhibits a user's libido. To avoid this users can lower dosages, but some anecdotally report that even extremely low doses of the drug can cause problems. If this is the case a less potent compound such as exemestane or anastrozole may be a more appropriate option.
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In general, Proviron is a relatively inexpensive and easily located product to find. Pharmaceutical grade Proviron is always going to be more expensive than the underground counterpart, but that is the way things go for almost all pharmaceutical products versus UGL-manufactured items. Schering Proviron in particular sells, on average, for around $ per tablet (25mg). Other pharmaceutical brands of Proviron can be lower priced, with some ranging around $ per tablet. Underground grade Proviron is known to be much cheaper for obvious reasons, with some being sold for as low as $ per tablet (25mg). Underground products are not manufactured to any standard, however, and some brands may manufacture tablets in different concentrations (20mg, 25mg, 50mg, or even 100mg), and so it can become quite difficult to gauge and judge current market prices because of this.