As this anabolic steroid is not very liver toxic, in-fact it is quite mild it can be used for extended periods of time; if you are not susceptible to DHT based side-effects you could reasonably supplement with Proviron the entire duration of your cycle. While it can be used for extended periods, as we will see dosing protocol can vary dramatically depending on the purpose for which it is used. If Proviron is being used simply as a quasi-anti-estrogen medication then a mere 25mg per day may be all you need but many will find 50mg to be needed if their cycle contains a high dosing of aromatizing steroids. For those who are supplementing for additional beneficial purposes higher doses may be needed; although 50mg will provide them solid effects a slightly higher bump may be needed. If you choose to use Proviron this is something you may need to play with as individual response will vary greatly. For the individual who supplements for the purpose of bridging, a rather common purpose of Proviron use, doses will necessarily be much higher, ranging from 100mg-150mg per day if the individual is going to obtain the desired effect and benefits.
42 subfertile male ambulatory patients were treated with Proviron. Moderate oligoastheno-teratozoospermia was the most common injury in sperm analysis. The treatment did not change the amount of plasma FSH, testosterone or prostate phosphatase. Acid phosphatase and citric acid of semen showed an increased activity with mesterolone treatment. The amount of fructose decreased, it is probably due to the increased number of spermatozoa, which need more fructose for their metabolism respectively. The sperm of 93% of the patients improved or stayed unchanged. 30% of the patients developed normozoospermia. 6 pregnancies were achieved