In three clinical trials primarily designed to assess the safety and immunogenicity of another vaccine, Menactra® [Meningococcal (Groups A, C, Y and W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine], participants were randomized to receive Menactra or Menomune - A/C/Y/W-135 vaccine, which was used as a control vaccine. In these three trials, 1519 children 2-10 years of age, 972 persons 11-18 years of age, and 1170 adults 18-55 years of age, respectively, received a dose of Menomune - A/C/Y/W-135 vaccine. Overall, of the children 210 years of age who received Menactra or Menomune - A/C/Y/W-135 vaccine, 68% were enrolled at US sites and 32% were enrolled at a Chilean site. The median ages of US and Chilean children were 6 and 5 years, respectively; overall, % were males and % were Caucasian. Among participants 11-55 years of age who received Menactra or Menomune - A/C/Y/W-135 vaccine, all were enrolled at US sites; % were female; % were Caucasian.
If a person is on an SSRI, and changes their diet or eats something that inhibits/blocks the enzyme system that metabolises the drugs…akathisia can explode in the head. It’s interesting to me that Stewart Dolin was well enough to go to a business lunch and shortly after that he committed suicide…I’m wondering what did he eat at that lunch? I was always at my most suicidal in the morning and I drink tea. Much later I found research that black teas inhibits all of the Cytochrome P450 liver enzyme system involved in metabolising these drugs.