Like other AAS, drostanolone is an agonist of the androgen receptor (AR).  It is not a substrate for 5α-reductase and is a poor substrate for 3α-hydroxysteroid dehydrogenase (3α-HSD), and therefore shows a high ratio of anabolic to androgenic activity.  As a DHT derivative, drostanolone is not a substrate for aromatase and hence cannot be aromatized into estrogenic metabolites .  While no data are available on the progestogenic activity of drostanolone, it is thought to have low or no such activity similarly to other DHT derivatives.  Since the drug is not 17α-alkylated , it is not known to cause hepatotoxicity . 
Q. Is it possible to have fibromyalgia in your feet and hands? Can you explain? I am very eager to know whether anybody is here with the symptoms of mine. My thumb hurts so much that it's difficult for me to write, and both my feet hurt when I put any weight on them. My hands and feet used to be the only parts of my body that didn't hurt. Is it possible to have fibromyalgia in your feet and hands? Can you explain? A. Calcium/magnesium
cod liver oil
flax seed oil
raw apple cider vinegar
avoid highly process foods, especially white sugar and white flour
However, in December 2004 the United States the 14-member Food and Drug Administration (FDA) advisory committee, plus voting consultants, for Reproductive Health Drugs unanimously rejected Procter and Gamble's fast-track request for Intrinsa citing concerns about off-label use . In Canada, post-menopausal women have been able to obtain government-approved testosterone treatment since 2002. In Australia, post-menopausal women can use Organon testosterone implants which have to be surgically inserted and last from three to six months.